Wednesday, September 21, 2016

ApexiCon E


Generic Name: diflorasone topical (dye FLOR a sone)

Brand Names: ApexiCon, ApexiCon E, Maxiflor, Psorcon E


What is ApexiCon E (diflorasone topical)?

Diflorasone is a topical (for the skin) steroid. It reduces the actions of chemicals in the body that cause inflammation, redness, and swelling.


Diflorasone topical is used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis.


Diflorasone topical may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about ApexiCon E (diflorasone topical)?


Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts or for longer than recommended. Topical steroid medicine can be absorbed through the skin, which may cause steroid side effects throughout the body.


Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to. Plastic film covering (such as plastic wrap) is sometimes used when treating psoriasis. Follow your doctor's instructions.

If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Covering the skin that is treated with diflorasone topical can increase the amount of medicine your skin absorbs, which may lead to unwanted side effects.


Do not use this medication on a child without a doctor's advice. Children are more likely to absorb large amounts of a topical steroid through the skin. Steroid absorption in children may cause unwanted side effects, or a delay in growth with long-term use. Talk with your doctor if you think your child is not growing at a normal rate while using this medication over a long treatment period. Contact your doctor if your condition does not improve, or if you develop signs of a bacterial, fungal, or viral skin infection.

What should I discuss with my healthcare provider before using ApexiCon E (diflorasone topical)?


Do not use this medication if you are allergic to diflorasone.

Before using diflorasone topical, tell your doctor if you are allergic to any drugs, or if you have any type of skin infection.


Also tell your doctor if you have diabetes. Topical steroid medicines absorbed through the skin may increase the glucose (sugar) levels in your blood or urine.


FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether diflorasone topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not use this medication on a child without a doctor's advice. Children are more likely to absorb large amounts of a topical steroid through the skin. Steroid absorption in children may cause unwanted side effects, or a delay in growth with long-term use. Talk with your doctor if you think your child is not growing at a normal rate while using this medication over a long treatment period.

How should I use ApexiCon E (diflorasone topical)?


Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts or for longer than recommended. Topical steroid medicine can be absorbed through the skin, which may cause steroid side effects throughout the body.


Wash your hands before and after using diflorasone topical, unless you are using the medication to treat the skin on your hands.

Apply a small amount to the affected area and rub it gently into the skin. Do not use this medication over a large area of skin.


Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to. Plastic film covering (such as plastic wrap, plastic gloves, or a shower cap) is sometimes used to cover areas of psoriasis that are treated with diflorasone topical. Follow your doctor's instructions.

Avoid plastic covering over skin lesions that are oozing or draining pus or any type of fluid.


If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Covering the skin that is treated with diflorasone topical can increase the amount of medicine your skin absorbs, which may lead to unwanted side effects.


Contact your doctor if your condition does not improve, or if you develop signs of a bacterial, fungal, or viral skin infection. It is important to use diflorasone topical regularly to get the most benefit.

If you are treating psoriasis, use the medication for at least a few days after the skin clears. Stopping too soon could cause a relapse.


To be sure this medication is not causing harmful effects with long-term use, you may need blood tests. Do not miss any scheduled appointments.


Store diflorasone topical at room temperature away from moisture and heat. Keep from freezing.

What happens if I miss a dose?


Use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and use the medicine at the next regularly scheduled time. Do not use extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of diflorasone is not expected to produce life-threatening symptoms. However, long-term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.


What should I avoid while using ApexiCon E (diflorasone topical)?


Diflorasone topical should not be used to treat any skin condition your doctor has not prescribed it for.


Avoid getting this medication in your eyes. If contact does occur, rinse with water. Do not use diflorasone topical on broken or infected skin. Also avoid using this medication in open wounds.

ApexiCon E (diflorasone topical) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have severe irritation of any treated skin, or if you show signs of absorbing diflorasone topical through your skin, such as:

  • blurred vision, or seeing halos around lights;




  • mood changes;




  • sleep problems (insomnia);




  • weight gain, puffiness in your face; or




  • muscle weakness, feeling tired.



Less serious side effects may include:



  • mild skin itching, burning, or dryness;




  • thinning or softening of your skin;




  • skin rash or irritation around your mouth;




  • swollen hair follicles;




  • changes in color of treated skin;




  • blisters, pimples, or crusting of treated skin; or




  • stretch marks.



This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect ApexiCon E (diflorasone topical)?


It is not likely that other drugs you take orally or inject will have an effect on topically applied diflorasone topical. But many drugs can interact with each other. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.



More ApexiCon E resources


  • ApexiCon E Side Effects (in more detail)
  • ApexiCon E Use in Pregnancy & Breastfeeding
  • ApexiCon E Drug Interactions
  • ApexiCon E Support Group
  • 0 Reviews for ApexiCon E - Add your own review/rating


  • Apexicon Cream MedFacts Consumer Leaflet (Wolters Kluwer)

  • Apexicon Prescribing Information (FDA)

  • Apexicon E Advanced Consumer (Micromedex) - Includes Dosage Information

  • Apexicon E Prescribing Information (FDA)

  • Florone Prescribing Information (FDA)

  • Psorcon Monograph (AHFS DI)

  • psorcon Prescribing Information (FDA)



Compare ApexiCon E with other medications


  • Atopic Dermatitis
  • Eczema
  • Psoriasis
  • Skin Rash
  • Urticaria


Where can I get more information?


  • Your pharmacist can provide more information about diflorasone topical.

See also: ApexiCon E side effects (in more detail)


Actoplus Met



Pronunciation: PYE-oh-GLI-ta-zone/met-FOR-min
Generic Name: Pioglitazone/Metformin
Brand Name: Actoplus Met

Actoplus Met may rarely cause a serious and sometimes fatal condition called lactic acidosis. Most of these cases have occurred in diabetic patients who also have certain kidney problems. The risk of lactic acidosis may be greater if you have liver problems, kidney problems, or heart failure. The risk may also be greater in patients who are elderly or who drink alcohol. Lab tests, including kidney function, may be performed while you take Actoplus Met.


Do not begin to take Actoplus Met if you are older than 80 years old unless lab tests show that you do not have decreased kidney function. Do not take it if you have severe infection or low blood oxygen levels, or are dehydrated. Tell your doctor if you take Actoplus Met before you have any surgery or lab procedures.


Contact your doctor right away if you notice symptoms such as muscle pain or tenderness, unusual drowsiness, dizziness or light-headedness, slow or irregular heartbeat, fast or difficult breathing, unusual stomach discomfort, or unusual weakness or tiredness. Contact your doctor right away if you start to feel unusually cold, or if you have a general feeling of being unwell.


Thiazolidinedione antidiabetics such as Actoplus Met may cause or worsen heart failure in some patients. Tell your doctor if you have a history of heart failure. Actoplus Met should not be used to treat patients with moderate to severe heart failure. You will be monitored for signs of heart failure when you start Actoplus Met and when your dose increases. Contact your doctor at once if you develop swelling of the hands, ankles, or feet; shortness of breath; or sudden, unexplained weight gain. Your doctor may need to stop your medicine or change your dose.





Actoplus Met is used for:

Treating type 2 diabetes. It is used along with diet and exercise. It may be used alone or with other antidiabetic medicines.


Actoplus Met is a biguanide and thiazolidinedione antidiabetic combination. It works by decreasing the amount of sugar the liver produces and the intestines absorb. It also helps to make your body more sensitive to the insulin that you naturally produce.


Do NOT use Actoplus Met if:


  • you are allergic to any ingredient in Actoplus Met

  • you have type 1 diabetes

  • you have bladder cancer or moderate to severe heart failure

  • you have a severe infection, low blood oxygen levels, kidney or liver problems, or high blood ketone or acid levels (eg, diabetic ketoacidosis), or you are severely dehydrated

  • you have had a stroke or a recent heart attack, or you are in shock

  • you are 80 years old or older and have not had a kidney function test

  • you will be having surgery or certain lab procedures

  • you have a history of liver problems, including jaundice (yellowing of the skin or eyes), during therapy with a similar medicine called troglitazone

Contact your doctor or health care provider right away if any of these apply to you.



Before using Actoplus Met:


Some medical conditions may interact with Actoplus Met. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a history of heart problems (eg, heart failure), abnormal liver function tests, lung or breathing problems, thyroid problems, stomach or bowel problems (eg, paralysis, blockage), adrenal or pituitary problems, eye or vision problems (eg, macular degeneration), bladder cancer, or lactic acidosis

  • if you have fluid retention or swelling problems, vomiting, diarrhea, poor health or nutrition, low blood calcium or vitamin B12 levels, or anemia, or if you are dehydrated

  • if you have an infection, fever, recent injury, or moderate to severe burns

  • if you have a history of bone fracture, weak bones (eg, osteoporosis), or low calcium intake

  • if you drink alcohol or have a history of alcohol abuse

  • if you will be having surgery or certain lab procedures

  • if you take a beta-blocker (eg, propranolol)

Some MEDICINES MAY INTERACT with Actoplus Met. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Calcium channel blockers (eg, nifedipine), corticosteroids (eg, prednisone), diuretics (eg, furosemide, hydrochlorothiazide), estrogen, hormonal contraceptives (eg, birth control pills), insulin, isoniazid, nicotinic acid, oral antidiabetics (eg, glipizide), phenothiazines (eg, chlorpromazine), phenytoin, sympathomimetics (eg, albuterol, pseudoephedrine), or thyroid hormones (eg, levothyroxine) because the risk of high or low blood sugar may be increased

  • Amiloride, cimetidine, digoxin, gemfibrozil, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, trimethoprim, or vancomycin because they may increase the risk of Actoplus Met's side effects

  • Rifampin because it may decrease Actoplus Met's effectiveness, resulting in high blood sugar

  • Anticoagulants (eg, warfarin) because their effectiveness may be decreased or the risk of their side effects may be increased by Actoplus Met

This may not be a complete list of all interactions that may occur. Ask your health care provider if Actoplus Met may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Actoplus Met:


Use Actoplus Met as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Actoplus Met comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Actoplus Met refilled.

  • Take Actoplus Met by mouth with meals.

  • Take Actoplus Met on a regular schedule to get the most benefit from it. Taking Actoplus Met at the same times each day will help you remember to take it.

  • Continue to take Actoplus Met even if you feel well. Do not miss any doses.

  • If you miss a dose of Actoplus Met, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Actoplus Met.



Important safety information:


  • Actoplus Met may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Actoplus Met with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Follow the diet and exercise program given to you by your health care provider.

  • Talk to your doctor of health care provider before you drink alcohol while you use Actoplus Met.

  • Tell your doctor or dentist that you take Actoplus Met before you receive any medical or dental care, emergency care, or surgery.

  • Do NOT take more than the recommended dose without checking with your doctor.

  • Be careful not to become dehydrated, especially during hot weather, while you are being active, or if you have vomiting or diarrhea. Dehydration may increase your risk of side effects from Actoplus Met.

  • Actoplus Met may cause ovulation in women who have not reached menopause but do not ovulate. Women who wish to avoid pregnancy should be sure to use effective birth control while using Actoplus Met.

  • Carry an ID card at all times that says you have diabetes. Check your blood sugar levels as directed by your doctor. If they are often higher or lower than they should be and you take Actoplus Met exactly as prescribed, tell your doctor.

  • Actoplus Met does not usually cause low blood sugar. Low blood sugar may be more likely to occur if you skip a meal, exercise heavily, or drink alcohol. It may also be more likely if you take Actoplus Met along with certain other medicines for diabetes (eg, sulfonylureas, insulin). It is a good idea to carry a reliable source of glucose (eg, tablets or gel) to treat low blood sugar. If this is not available, you should eat or drink a quick source of sugar like table sugar, honey, candy, orange juice, or non-diet soda. This will raise your blood sugar level quickly. Tell your doctor right away if this happens. To prevent low blood sugar, eat meals at the same time each day and do not skip meals.

  • Fever, infection, injury, or surgery may increase your risk for high or low blood sugar levels. If any of these occur, check your blood sugar closely and tell your doctor right away.

  • Actoplus Met may commonly cause stomach upset, indigestion, nausea, or diarrhea at the beginning of treatment. If you develop unusual or unexpected stomach problems, or if you develop stomach problems later during treatment, contact your doctor at once. This may be a sign of lactic acidosis.

  • An increased incidence of bone fracture has been reported in women who take Actoplus Met. Tell your doctor if you have a history of bone fracture, low calcium intake, or weak bones (eg, osteoporosis). Tell your doctor right away if you experience any unusual bone pain.

  • Actoplus Met may be associated with an increased risk of bladder cancer. Tell your doctor right away if you notice symptoms that could be associated with bladder cancer (eg, a red color or blood in the urine, difficult or painful urination, an increased need to urinate). Discuss any questions or concerns with your doctor.

  • Lab tests, including kidney and liver function, fasting blood glucose, hemoglobin A1c, blood counts, and eye examinations, may be performed while you use Actoplus Met. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

  • Use Actoplus Met with caution in the ELDERLY; they may be more sensitive to its effects. Low blood sugar levels may also be more difficult to recognize in the elderly.

  • Actoplus Met should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Actoplus Met while you are pregnant. It is not known if Actoplus Met is found in breast milk. Do not breast-feed while taking Actoplus Met.


Possible side effects of Actoplus Met:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Cold-like symptoms; diarrhea; headache; indigestion; mild weight gain; nausea; stomach upset.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision or other vision changes; bone pain; chest pain or discomfort; dark urine; difficult or painful urination; dizziness or light-headedness; fainting; fast or difficult breathing; feeling of being unusually cold; general feeling of being unwell; muscle pain or weakness; pale stools; persistent loss of appetite; severe or persistent headache, nausea, or vomiting; shortness of breath; slow or irregular heartbeat; sudden, unexplained weight gain; swelling of the hands, ankles, or feet; unusual stomach pain or discomfort; unusual drowsiness; unusual tiredness or weakness; yellowing of the eyes or skin.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Actoplus Met side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include dizziness or light-headedness; fast or difficult breathing; feeling of being unusually cold; general feeling of being unwell; muscle pain or tenderness; slow or irregular heartbeat; unusual drowsiness; unusual stomach discomfort; unusual weakness or tiredness.


Proper storage of Actoplus Met:

Store Actoplus Met between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in bathroom. Keep Actoplus Met out of the reach of children and away from pets.


General information:


  • If you have any questions about Actoplus Met, please talk with your doctor, pharmacist, or other health care provider.

  • Actoplus Met is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • If using Actoplus Met for an extended period of time, obtain refills before your supply runs out.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Actoplus Met. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Actoplus Met resources


  • Actoplus Met Side Effects (in more detail)
  • Actoplus Met Dosage
  • Actoplus Met Use in Pregnancy & Breastfeeding
  • Drug Images
  • Actoplus Met Drug Interactions
  • Actoplus Met Support Group
  • 6 Reviews for Actoplus Met - Add your own review/rating


  • Actoplus Met Prescribing Information (FDA)

  • Actoplus Met Advanced Consumer (Micromedex) - Includes Dosage Information

  • Actoplus Met Consumer Overview

  • Actoplus Met XR Prescribing Information (FDA)



Compare Actoplus Met with other medications


  • Diabetes, Type 2

Acuflex


Generic Name: acetaminophen and phenyltoloxamine (a seet a MIN oh fen and FEN il toe LOX a meen)

Brand Names: Aceta-Gesic, Acuflex, Alpain, Apagesic, BeFlex, BP Poly-650, Dologesic, Flextra-650, Flextra-DS, Hyflex-650, Hyflex-DS, Lagesic, Major-gesic, Percogesic, Phenagesic, Phenylgesic, Q Flex, Relagesic, RhinoFlex, RhinoFlex 650, Staflex, Vistra, Vitoxapap, Zgesic


What is acetaminophen and phenyltoloxamine?

Acetaminophen is a pain reliever and a fever reducer.


Phenyltoloxamine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.


Acetaminophen and phenyltoloxamine is used to treat runny nose, sneezing, and pain or fever caused by the common cold, flu, or seasonal allergies.


Acetaminophen and phenyltoloxamine may also be used for purposes not listed in this medication guide.


What is the most important information I should know about acetaminophen and phenyltoloxamine?


Do not take this medication without a doctor's advice if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. You may not be able to take medicine that contains acetaminophen. Do not use cold medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have liver or kidney disease, diabetes, glaucoma, urination problems, an enlarged prostate, heart disease, high blood pressure, a stomach ulcer, or an overactive thyroid.


Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death. Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen. Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.

What should I discuss with my healthcare provider before taking acetaminophen and phenyltoloxamine?


You should not take this medication if you are allergic to acetaminophen or phenyltoloxamine. Do not take this medication without a doctor's advice if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. You may not be able to take medicine that contains acetaminophen. Do not use acetaminophen and phenyltoloxamine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:


  • liver disease or a history of alcoholism;


  • kidney disease;




  • diabetes;




  • glaucoma;




  • urination problems;




  • an enlarged prostate;




  • heart disease or high blood pressure;




  • a stomach ulcer; or




  • an overactive thyroid.




It is not known whether acetaminophen and phenyltoloxamine is harmful to an unborn baby. Do not take this medication without telling your doctor if you are pregnant. Acetaminophen and phenyltoloxamine can pass into breast milk and may harm a nursing baby. Do not take this medication without telling your doctor if you are breast-feeding a baby.

How should I take acetaminophen and phenyltoloxamine?


Use exactly as directed on the label, or as prescribed by your doctor. Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death. Cold or allergy medicine is usually taken only for a short time until your symptoms clear up.

One tablet of this medicine may contain up to 650 mg of acetaminophen. Know the amount of acetaminophen in the specific product you are taking.


Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking the pill may cause too much of the drug to be released at one time.

Call your doctor if your symptoms do not improve, or if you have a fever for longer than 3 days.


This medication can cause unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.


Store at room temperature away from moisture and heat.

What happens if I miss a dose?


Since cold or allergy medicine is taken when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of acetaminophen can be fatal.

The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.


Overdose symptoms may also include feeling very restless, extreme drowsiness, warmth or tingly feeling, or seizure (convulsions).


What should I avoid while taking acetaminophen and phenyltoloxamine?


This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen. Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP. Avoid becoming overheated or dehydrated during exercise and in hot weather. Phenyltoloxamine can decrease sweating and you may be more prone to heat stroke.

Acetaminophen and phenyltoloxamine side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have a serious side effect such as:

  • fast, pounding, or uneven heartbeat;




  • confusion, hallucinations, unusual thoughts or behavior;




  • severe dizziness, anxiety, restless feeling, nervousness;




  • urinating less than usual or not at all;




  • nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay colored stools, jaundice (yellowing of the skin or eyes); or




  • easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms.



Less serious side effects may include:



  • dizziness, drowsiness;




  • blurred vision;




  • dry mouth, nose, or throat;




  • mild stomach pain, constipation; or




  • problems with memory or concentration.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect acetaminophen and phenyltoloxamine?


Before using this medicine, tell your doctor if you regularly use other medicines that make you sleepy (such as other cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by phenyltoloxamine.

There may be other drugs that can interact with acetaminophen and phenyltoloxamine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Acuflex resources


  • Acuflex Side Effects (in more detail)
  • Acuflex Use in Pregnancy & Breastfeeding
  • Acuflex Drug Interactions
  • Acuflex Support Group
  • 0 Reviews for Acuflex - Add your own review/rating


  • Acuflex MedFacts Consumer Leaflet (Wolters Kluwer)

  • Acuflex Consumer Overview

  • Lagesic Controlled-Release Tablets MedFacts Consumer Leaflet (Wolters Kluwer)

  • Percogesic Consumer Overview



Compare Acuflex with other medications


  • Cold Symptoms
  • Headache
  • Influenza
  • Pain


Where can I get more information?


  • Your pharmacist can provide more information about acetaminophen and phenyltoloxamine.

See also: Acuflex side effects (in more detail)


Aldex-CT


Generic Name: diphenhydramine and phenylephrine (DYE fen HYE dra meenand FEN il EFF rin)

Brand Names: Alahist LQ, Aldex-CT, Children's Triacting Night Time, D-Tann, Dimetapp Nighttime Cold & Congestion, Diphenmax D, Dytan-D, PediaCare Children's Allergy & Cold, Robitussin Night Time Cough & Cold, Robitussin Night Time Cough & Cold Children's, Robitussin Night Time Cough & Cold Pediatric, Triaminic Night Time Cold & Cough


What is Aldex-CT (diphenhydramine and phenylephrine)?

Diphenhydramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.


Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).


The combination of diphenhydramine and phenylephrine is used to treat runny or stuffy nose, sneezing, watery eyes, and sinus congestion caused by allergies, the common cold, or the flu.


Diphenhydramine and phenylephrine may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about Aldex-CT (diphenhydramine and phenylephrine)?


Do not give this medication to a child younger than 2 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, or cough suppressant. Avoid drinking alcohol while you are taking this medication. It can add to drowsiness caused by an antihistamine.

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor's advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.


This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Tell your doctor if you regularly use other medicines that make you sleepy (such as other cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by diphenhydramine.

What should I discuss with my healthcare provider before taking Aldex-CT (diphenhydramine and phenylephrine)?


You should not use this medication if you are allergic to diphenhydramine or phenylephrine.

Before taking this medication, tell your doctor if you are allergic to any drugs, or if you have:



  • asthma;




  • heart disease or high blood pressure;




  • diabetes;




  • a thyroid disorder;




  • glaucoma;




  • kidney disease;




  • an enlarged prostate; or




  • problems with urination.



If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.


This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. This medication may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Older adults may be more likely to have side effects from this medication.

Artificially-sweetened liquid forms of cold medicine may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.


How should I take Aldex-CT (diphenhydramine and phenylephrine)?


Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Cold medicine is usually taken only for a short time until your symptoms clear up.


Do not give this medication to a child younger than 2 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.


Make sure you chew the chewable tablet before you swallow it.


This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.


Store this medicine at room temperature, away from heat, light, and moisture.

What happens if I miss a dose?


Since cold or allergy medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include feeling restless or nervous, nausea, vomiting, stomach pain, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).


What should I avoid while taking Aldex-CT (diphenhydramine and phenylephrine)?


Avoid drinking alcohol while you are taking this medication. It can add to drowsiness caused by an antihistamine. Tell your doctor if you regularly use other medicines that make you sleepy (such as other cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by diphenhydramine.

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor's advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.


This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid becoming overheated or dehydrated during exercise and in hot weather.


Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. Antihistamines, decongestants, and cough suppressants are contained in many medicines available over the counter. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, or cough suppressant.

Aldex-CT (diphenhydramine and phenylephrine) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • fast, pounding, or uneven heartbeat;




  • confusion, hallucinations, unusual thoughts or behavior;




  • urinating less than usual or not at all;




  • severe dizziness, anxiety, restless feeling, or nervousness;




  • easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms;




  • increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure); or




  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).



Less serious side effects may include:



  • blurred vision;




  • dry mouth;




  • nausea, stomach pain, constipation;




  • dizziness, drowsiness;




  • problems with memory or concentration;




  • ringing in your ears;




  • mild loss of appetite;




  • warmth, tingling, or redness under your skin;




  • feeling excited or restless;




  • sleep problems (insomnia); or




  • skin rash or itching.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Aldex-CT (diphenhydramine and phenylephrine)?


Tell your doctor about all other medications you use, especially:



  • medicines to treat high blood pressure;




  • a beta-blocker such as atenolol (Tenormin), carteolol (Cartrol), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal), sotalol (Betapace), timolol (Blocadren), and others;




  • antidepressants such as amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Janimine, Tofranil), and others; or




  • an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate).



This list is not complete and there may be other drugs that can interact with diphenhydramine and phenylephrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.



More Aldex-CT resources


  • Aldex-CT Side Effects (in more detail)
  • Aldex-CT Use in Pregnancy & Breastfeeding
  • Aldex-CT Drug Interactions
  • Aldex-CT Support Group
  • 0 Reviews for Aldex-CT - Add your own review/rating


  • Alahist LQ Liquid MedFacts Consumer Leaflet (Wolters Kluwer)

  • D-Tann Chewable Tablets MedFacts Consumer Leaflet (Wolters Kluwer)



Compare Aldex-CT with other medications


  • Cold Symptoms
  • Hay Fever
  • Sinusitis


Where can I get more information?


  • Your pharmacist can provide more information about diphenhydramine and phenylephrine.

See also: Aldex-CT side effects (in more detail)


Amoxicillin/Clavulanate Extended-Release Tablets


Pronunciation: a-MOX-i-SIL-in/KLAV-ue-la-nate
Generic Name: Amoxicillin/Clavulanate
Brand Name: Augmentin XR


Amoxicillin/Clavulanate Extended-Release Tablets are used for:

Treating infections caused by certain bacteria.


Amoxicillin/Clavulanate Extended-Release Tablets are a penicillin antibiotic. It works by killing sensitive bacteria.


Do NOT use Amoxicillin/Clavulanate Extended-Release Tablets if:


  • you are allergic to any ingredient in Amoxicillin/Clavulanate Extended-Release Tablets or another penicillin antibiotic (eg, ampicillin)

  • you have a history of liver problems or yellowing of the eyes or skin caused by Amoxicillin/Clavulanate Extended-Release Tablets

  • you have severe kidney problems or are on dialysis

  • you have infectious mononucleosis (mono)

  • you have recently received or will be receiving a live oral typhoid vaccine

Contact your doctor or health care provider right away if any of these apply to you.



Before using Amoxicillin/Clavulanate Extended-Release Tablets:


Some medical conditions may interact with Amoxicillin/Clavulanate Extended-Release Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a history of allergies, asthma, hay fever, or hives

  • if you have had a severe allergic reaction (eg, severe rash, hives, breathing difficulties, dizziness) to a cephalosporin (eg, cephalexin) or another beta-lactam antibiotic (eg, imipenem)

  • if you have kidney problems or gonorrhea

  • if you have a history of liver problems or yellowing of the eyes or skin

  • if you are on a low-salt (sodium) diet

Some MEDICINES MAY INTERACT with Amoxicillin/Clavulanate Extended-Release Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Anticoagulants (eg, warfarin) because the risk of bleeding may be increased

  • Probenecid because it may increase the amount of Amoxicillin/Clavulanate Extended-Release Tablets in your blood

  • Chloramphenicol, macrolide antibiotics (eg, erythromycin), sulfonamides (eg, sulfamethoxazole), or tetracycline antibiotics (eg, doxycycline) because they may decrease Amoxicillin/Clavulanate Extended-Release Tablets's effectiveness

  • Allopurinol because the risk of rash may be increased

  • Methotrexate because the risk of its side effects may be increased by Amoxicillin/Clavulanate Extended-Release Tablets

  • Live oral typhoid vaccine or hormonal birth control (eg, birth control pills) because their effectiveness may be decreased by Amoxicillin/Clavulanate Extended-Release Tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if Amoxicillin/Clavulanate Extended-Release Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Amoxicillin/Clavulanate Extended-Release Tablets:


Use Amoxicillin/Clavulanate Extended-Release Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Take Amoxicillin/Clavulanate Extended-Release Tablets by mouth at the start of a meal.

  • Swallow Amoxicillin/Clavulanate Extended-Release Tablets whole. Do not break, crush, or chew before swallowing. If you have difficulty swallowing the whole tablet, this tablet may be broken in half.

  • To clear up your infection completely, take Amoxicillin/Clavulanate Extended-Release Tablets for the full course of treatment. Keep taking it even if you feel better in a few days.

  • If you miss a dose of Amoxicillin/Clavulanate Extended-Release Tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Amoxicillin/Clavulanate Extended-Release Tablets.



Important safety information:


  • Amoxicillin/Clavulanate Extended-Release Tablets may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Amoxicillin/Clavulanate Extended-Release Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Amoxicillin/Clavulanate Extended-Release Tablets only works against bacteria; it does not treat viral infections (eg, the common cold).

  • Be sure to use Amoxicillin/Clavulanate Extended-Release Tablets for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

  • Long-term or repeated use of Amoxicillin/Clavulanate Extended-Release Tablets may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.

  • Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.

  • Hormonal birth control (eg, birth control pills) may not work as well while you are using Amoxicillin/Clavulanate Extended-Release Tablets. To prevent pregnancy, use an extra form of birth control (eg, condoms).

  • Amoxicillin/Clavulanate Extended-Release Tablets has sodium in it. If you are on a low-salt (sodium) diet, include this when you count your daily intake of sodium.

  • Brown, yellow, or gray tooth discoloration has occurred rarely in some patients taking Amoxicillin/Clavulanate Extended-Release Tablets. It occurred most often in children. The discoloration was reduced or removed by brushing or dental cleaning in most cases. Contact your doctor if you experience this effect.

  • Diabetes patients - Amoxicillin/Clavulanate Extended-Release Tablets may cause the results of some tests for urine glucose to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine.

  • Lab tests, including liver function, kidney function, and complete blood cell counts, may be performed if you use Amoxicillin/Clavulanate Extended-Release Tablets for a long period of time. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

  • Use Amoxicillin/Clavulanate Extended-Release Tablets with caution in the ELDERLY; they may be more sensitive to its effects, especially patients with kidney problems.

  • Amoxicillin/Clavulanate Extended-Release Tablets should be used with extreme caution in CHILDREN weighing less than 40 kilograms (88 pounds); safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Amoxicillin/Clavulanate Extended-Release Tablets while you are pregnant. Amoxicillin/Clavulanate Extended-Release Tablets are found in breast milk. If you are or will be breast-feeding while you use Amoxicillin/Clavulanate Extended-Release Tablets, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Amoxicillin/Clavulanate Extended-Release Tablets:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Diarrhea; nausea; vomiting.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bloody stools; confusion; dark urine; fever, chills, or persistent sore throat; red, swollen, blistered, or peeling skin; seizures; severe or persistent diarrhea; stomach pain or cramps; unusual bruising or bleeding; vaginal discharge or irritation; yellowing of the skin or eyes.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Amoxicillin/Clavulanate side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include decreased urination; severe nausea, vomiting, or diarrhea; stomach pain; unusual drowsiness.


Proper storage of Amoxicillin/Clavulanate Extended-Release Tablets:

Store at or below 77 degrees F (25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Amoxicillin/Clavulanate Extended-Release Tablets out of the reach of children and away from pets.


General information:


  • If you have any questions about Amoxicillin/Clavulanate Extended-Release Tablets, please talk with your doctor, pharmacist, or other health care provider.

  • Amoxicillin/Clavulanate Extended-Release Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Amoxicillin/Clavulanate Extended-Release Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Amoxicillin/Clavulanate resources


  • Amoxicillin/Clavulanate Side Effects (in more detail)
  • Amoxicillin/Clavulanate Dosage
  • Amoxicillin/Clavulanate Use in Pregnancy & Breastfeeding
  • Drug Images
  • Amoxicillin/Clavulanate Drug Interactions
  • Amoxicillin/Clavulanate Support Group
  • 69 Reviews for Amoxicillin/Clavulanate - Add your own review/rating


Compare Amoxicillin/Clavulanate with other medications


  • Aspiration Pneumonia
  • Bacterial Infection
  • Bronchitis
  • Febrile Neutropenia
  • Kidney Infections
  • Melioidosis
  • Otitis Media
  • Pneumonia
  • Sinusitis
  • Skin and Structure Infection
  • Skin Infection
  • Small Bowel Bacterial Overgrowth
  • Strep Throat
  • Upper Respiratory Tract Infection
  • Urinary Tract Infection

Albalon


Generic Name: naphazoline ophthalmic (na FAZ oh leen)

Brand Names: AK-Con, Albalon, Allerest Eye Drops, Clear Eyes, Degest 2, Estivin II, Nafazair, Naphcon, Naphcon Forte, VasoClear, Vasocon


What is Albalon (naphazoline ophthalmic)?

Naphazoline ophthalmic causes constriction of blood vessels in the eyes. It also decreases itching and irritation of the eyes.


Naphazoline ophthalmic is used to relieve redness, burning, irritation, and dryness of the eye caused by wind, sun, and other minor irritants.

Naphazoline ophthalmic may also be used for purposes other than those listed in this medication guide.


What is the most important information I should know about Albalon (naphazoline ophthalmic)?


Do not touch the dropper to any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in the eye.

If you wear contact lenses, remove them before applying naphazoline ophthalmic. Ask your doctor if contact lenses can be reinserted after application of the medication. Naphazoline ophthalmic may contain a preservative (benzalkonium chloride), which may cause discoloration of contact lenses.


Do not use naphazoline ophthalmic more often or continuously for longer than 48 to 72 hours without consulting a doctor. Chronic use of this medication may damage the blood vessels (veins and arteries) in the eyes. Consult a doctor if your symptoms do not improve or appear to worsen.

What should I discuss with my healthcare provider before using Albalon (naphazoline ophthalmic)?


Do not use naphazoline ophthalmic if you have glaucoma, except under the supervision of your doctor.

Before using this medication, tell your doctor if you



  • have any type of heart condition, including high blood pressure;




  • take any medicines to treat a heart condition;




  • have asthma;




  • have diabetes; or




  • have thyroid problems.



You may not be able to use naphazoline ophthalmic, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.


If you wear contact lenses, remove them before applying naphazoline ophthalmic. Ask your doctor if contact lenses can be reinserted after application of the medication. Naphazoline ophthalmic may contain a preservative (benzalkonium chloride), which may cause discoloration of contact lenses.


Naphazoline ophthalmic is in the FDA pregnancy category C. This means that it is not known whether naphazoline ophthalmic will be harmful to an unborn baby. Do not use this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether naphazoline passes into breast milk. Do not use naphazoline ophthalmic without first talking to your doctor if you are breast-feeding a baby.

How should I use Albalon (naphazoline ophthalmic)?


Use naphazoline eye drops exactly as directed by your doctor, or follow the directions that accompany the package. If you do not understand these instructions, ask your doctor, pharmacist, or nurse to explain them to you.


Wash your hands before and after using the eye drops.


To apply the eye drops:


If you wear contact lenses, remove them before applying naphazoline ophthalmic. Ask your doctor if contact lenses can be reinserted after application of the medication. Naphazoline ophthalmic may contain a preservative (benzalkonium chloride), which may cause discoloration of contact lenses.



  • Tilt the head back slightly and pull down on the lower eyelid. Position the dropper above the eye. Look up and away from the dropper. Squeeze out a drop and close the eye. Apply gentle pressure to the inside corner of the eye (near the nose) for about 1 minute to prevent the liquid from draining down your tear duct. Repeat the process in the other eye if needed..




Do not use naphazoline ophthalmic more often or continuously for longer than 48 to 72 hours without consulting a doctor. Chronic use of this medication may damage the blood vessels (veins and arteries) in the eyes. Consult a doctor if your symptoms do not improve or appear to worsen. Do not touch the dropper to any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in the eye. Do not use any eye drop that is discolored or has particles in it. Store naphazoline ophthalmic at room temperature away from moisture and heat. Keep the bottle properly capped.

What happens if I miss a dose?


Apply the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and apply the next one as directed. Do not use a double dose of this medication.


What happens if I overdose?


An overdose of this medication is unlikely to be harmful. If you do suspect an overdose, or if the drops have been ingested (taken by mouth), contact an emergency room or poison control center for advice.


What should I avoid while using Albalon (naphazoline ophthalmic)?


Do not touch the dropper to any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in the eye.

If you wear contact lenses, remove them before applying naphazoline ophthalmic. Ask your doctor if contact lenses can be reinserted after application of the medication. Naphazoline ophthalmic may contain a preservative (benzalkonium chloride), which may cause discoloration of contact lenses.


Do not use naphazoline ophthalmic more often or continuously for longer than 48 to 72 hours without consulting a doctor. Chronic use of this medication may damage the blood vessels (veins and arteries) in the eyes. Consult a doctor if your symptoms do not improve or appear to worsen.

Albalon (naphazoline ophthalmic) side effects


If you experience any of the following serious side effects, stop using naphazoline ophthalmic and seek emergency medical attention or contact your doctor immediately:



  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, face, or tongue; or hives);




  • an irregular or fast heart rate; or




  • high blood pressure (severe headache, blurred vision, or flushed skin).



Other, less serious side effects may be more likely to occur. Continue to use naphazoline ophthalmic and talk to your doctor if you experience



  • burning, stinging, pain, or increased redness of the eye;




  • tearing or blurred vision;




  • headache;




  • tremor;




  • nausea;




  • sweating;




  • nervousness;




  • dizziness; or




  • drowsiness.



Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Albalon (naphazoline ophthalmic)?


Do not use other eye medications during treatment with naphazoline ophthalmic except under the direction of your doctor.


Although drug interactions between naphazoline ophthalmic and drugs taken by mouth are not expected, they can occur. Before using this medication, tell your doctor if you are taking any of the following medicines:



  • a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil); or




  • a beta-blocker such as propranolol (Inderal), metoprolol (Lopressor, Toprol XL), or labetalol (Normodyne, Trandate).



You may not be able to use naphazoline ophthalmic, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.


Drugs other than those listed here may also interact with naphazoline ophthalmic. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.



More Albalon resources


  • Albalon Side Effects (in more detail)
  • Albalon Use in Pregnancy & Breastfeeding
  • Albalon Drug Interactions
  • Albalon Support Group
  • 0 Reviews for Albalon - Add your own review/rating


  • Albalon Advanced Consumer (Micromedex) - Includes Dosage Information

  • Albalon Prescribing Information (FDA)

  • Clear Eyes Drops MedFacts Consumer Leaflet (Wolters Kluwer)

  • Naphcon Drops MedFacts Consumer Leaflet (Wolters Kluwer)

  • Naphcon Prescribing Information (FDA)

  • Naphcon Forte Prescribing Information (FDA)

  • Vasocon Prescribing Information (FDA)



Compare Albalon with other medications


  • Eye Dryness/Redness
  • Eye Redness/Itching


Where can I get more information?


  • Your pharmacist has additional information about naphazoline ophthalmic written for health professionals that you may read.

See also: Albalon side effects (in more detail)


Augmentin ES-600


Generic Name: amoxicillin and clavulanate (Oral route)


a-mox-i-SIL-in, KLAV-ue-la-nate poe-TAS-ee-um


Commonly used brand name(s)

In the U.S.


  • Amoclan

  • Augmentin

  • Augmentin ES-600

  • Augmentin XR

In Canada


  • Alti-Amoxi Clav

  • Apo-Amoxi Clav

  • Novo-Clavamoxin 125

  • Novo-Clavamoxin 250

  • Ratio-Amoxi Clav 250f

Available Dosage Forms:


  • Tablet

  • Tablet, Extended Release

  • Powder for Suspension

  • Tablet, Chewable

Therapeutic Class: Antibiotic


Pharmacologic Class: Penicillin, Aminopenicillin


Uses For Augmentin ES-600


Amoxicillin and clavulanate combination is used to treat bacterial infections in many different parts of the body.


Amoxicillin and clavulanate combination is an antibiotic that belongs to the group of medicines known as penicillins and beta-lactamase inhibitors. It works by killing the bacteria and preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.


This medicine is available only with your doctor's prescription.


Before Using Augmentin ES-600


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of amoxicillin and clavulanate chewable tablets and oral suspension in children.


Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of amoxicillin and clavulanate tablets in children weighing 40 kilograms (kg) or more. However, safety and efficacy have not been established in children weighing less than 40 kg.


Appropriate studies have not been performed on the relationship of age to the effects of amoxicillin and clavulanate extended-release tablets in teenagers and children younger than 16 years of age. Safety and efficacy have not been established.


Geriatric


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of amoxicillin and clavulanate combination in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require an adjustment in the dose for patients receiving amoxicillin and clavulanate combination.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersBAnimal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding


Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Methotrexate

  • Venlafaxine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Acenocoumarol

  • Desogestrel

  • Dienogest

  • Drospirenone

  • Estradiol Cypionate

  • Estradiol Valerate

  • Ethinyl Estradiol

  • Ethynodiol Diacetate

  • Etonogestrel

  • Khat

  • Levonorgestrel

  • Medroxyprogesterone Acetate

  • Mestranol

  • Norelgestromin

  • Norethindrone

  • Norgestimate

  • Norgestrel

  • Probenecid

  • Warfarin

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Diarrhea or

  • Liver disease—Use with caution. May make these conditions worse.

  • Kidney disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

  • Kidney disease, severe—The extended-release tablets should not be used in patients with this condition.

  • Liver disease, history of with amoxicillin and clavulanate combination or

  • Mononucleosis ("mono")—Should not be used in patients with these conditions.

  • Phenylketonuria (PKU)—The chewable tablet and oral suspension contain phenylalanine, which can make this condition worse.

Proper Use of amoxicillin and clavulanate

This section provides information on the proper use of a number of products that contain amoxicillin and clavulanate. It may not be specific to Augmentin ES-600. Please read with care.


Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.


You may take this medicine with or without meals. However, it is best to take this medicine at the start of a meal or snack to avoid an upset stomach.


Swallow the extended-release tablet whole. Do not crush, break, or chew it.


If you are using the chewable tablets, chew the tablet completely before swallowing.


There are certain flavors that can be mixed with the oral suspension to make it taste better. If you or your child do not like the taste of this medicine, ask your pharmacist about these flavorings.


Keep the oral suspension refrigerated. Shake it well before measuring the dose. Use a dosing spoon or medicine dropper to measure the dose. The average household teaspoon may not hold the right amount of liquid. Rinse the dosing spoon or dropper with water after each use.


Do not change brands or dosage forms of amoxicillin and clavulanate combination without first checking with your doctor. Different products may not work the same way. If you refill your medicine and it looks different, ask your pharmacist about the change.


Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For bacterial infections:
    • For oral dosage form (chewable tablets, suspension):
      • Adults, teenagers, and children weighing 40 kilograms (kg) or more—250 to 500 milligrams (mg) every eight hours or 500 to 875 mg every twelve hours.

      • Children and infants above 3 months of age and weighing less than 40 kilograms (kg)—Dose is based on body weight and must be determined by your doctor. The usual dose is 20 to 40 milligrams (mg) per kilogram (kg) of body weight per day (mg/kg/day), divided and given every 8 hours, or 25 to 90 mg/kg/day, divided and given every 12 hours.

      • Infants younger than 3 months of age—Dose is based on body weight and must be determined by your doctor. The usual dose is 30 milligrams (mg) per kilogram (kg) of body weight per day, divided and given every 12 hours.


    • For oral dosage form (extended-release tablets):
      • Adults—2000 milligrams (mg) every 12 hours.

      • Children—Use and dose must be determined by your doctor.


    • For oral dosage form (tablets):
      • Adults, teenagers, and children weighing 40 kilograms (kg) or more—250 to 500 milligrams (mg) every eight hours or 500 to 875 mg every twelve hours.

      • Children weighing less than 40 kilograms (kg)—Use and dose must be determined by your doctor.



Missed Dose


If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Store the chewable tablets, regular tablets, and extended-release tablets at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Store the oral suspension in the refrigerator. Throw away any unused portion after 10 days. Keep from freezing.


Precautions While Using Augmentin ES-600


If your symptoms do not improve within a few days, or if they become worse, check with your doctor.


This medicine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and require immediate medical attention. Call your doctor right away if you or your child have itching; hives; hoarseness; shortness of breath; trouble with breathing; trouble with swallowing; or any swelling of your hands, face, or mouth after you receive this medicine.


Amoxicillin and clavulanate combination may cause diarrhea, and in some cases it can be severe. Do not take any medicine to treat diarrhea without first checking with your doctor. Diarrhea medicines may make the diarrhea worse or make it last longer. If you have any questions about this or if mild diarrhea continues or gets worse, check with your doctor.


In some young patients, tooth discoloration may occur while using this medicine. The teeth may appear to have brown, yellow, or gray stains. To help prevent this, brush and floss your teeth regularly or have a dentist clean your teeth.


Amoxicillin and clavulanate combination may decrease the effects of some oral contraceptives (birth control pills). To avoid an unwanted pregnancy, it is a good idea to use additional contraceptive measures with your pills (e.g., condoms, a diaphragm, or a contraceptive foam or jelly) while using this medicine.


Before you or your child have any medical tests, tell the doctor in charge that you are taking this medicine. The results of some tests may be affected by this medicine.


Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.


Augmentin ES-600 Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


Less common
  • Hives or welts

  • itching

  • itching of the vagina or genital area

  • pain during sexual intercourse

  • redness of the skin

  • skin rash

  • thick, white vaginal discharge with no odor or with a mild odor

Rare
  • Bloody or cloudy urine

  • fever

  • greatly decreased frequency of urination or amount of urine

  • seizures

  • swelling of the feet or lower legs

Incidence not known
  • Abdominal or stomach cramps or tenderness

  • back, leg, or stomach pains

  • black, hairy tongue

  • black, tarry stools

  • bleeding gums

  • blistering, peeling, or loosening of the skin

  • bloating

  • blood in the stools

  • bloody nose

  • chest pain

  • chills

  • clay-colored stools

  • cough or hoarseness

  • cracks in the skin

  • dark urine

  • diarrhea

  • diarrhea, watery and severe, which may also be bloody

  • difficulty with breathing

  • difficulty with moving

  • difficulty with swallowing

  • dizziness

  • fast heartbeat

  • fever with or without chills

  • general body swelling

  • general feeling of tiredness or weakness

  • headache

  • heavier menstrual periods

  • increased thirst

  • joint or muscle pain

  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

  • light-colored stools

  • loss of appetite

  • loss of heat from the body

  • lower back or side pain

  • muscle stiffness

  • nausea or vomiting

  • pain

  • pain, swelling, or redness in the joints

  • painful or difficult urination

  • pale skin

  • pinpoint red spots on the skin

  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

  • rash

  • red skin lesions, often with a purple center

  • red, irritated eyes

  • red, swollen skin

  • scaly skin

  • shortness of breath

  • sore throat

  • sores, ulcers, or white spots on the lips or in the mouth

  • swollen glands

  • tightness in the chest

  • troubled breathing with exertion

  • unpleasant breath odor

  • unusual bleeding or bruising

  • unusual tiredness or weakness

  • unusual weight loss

  • upper right abdominal pain

  • vomiting of blood

  • wheezing

  • white patches in the mouth or throat or on the tongue

  • white patches with diaper rash

  • yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:


Symptoms of overdose
  • Abdominal or stomach pain

  • bloody or cloudy urine

  • diarrhea

  • fever

  • greatly decreased frequency of urination or amount of urine

  • pain or burning while urinating

  • skin rash

  • sleepiness

  • swelling of the feet or lower legs

  • vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


Rare
  • Anxiety

  • dry mouth

  • hyperventilation

  • irregular heartbeats

  • irritability

  • nervousness

  • restlessness

  • shaking

  • sleeplessness

  • tooth discoloration

  • trouble sitting still

  • trouble with sleeping

  • unable to sleep

Incidence not known
  • Burning feeling in the chest or stomach

  • indigestion

  • redness, swelling, or soreness of the tongue

  • stomach upset

  • swelling or inflammation of the mouth

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Augmentin ES-600 side effects (in more detail)



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More Augmentin ES-600 resources


  • Augmentin ES-600 Side Effects (in more detail)
  • Augmentin ES-600 Use in Pregnancy & Breastfeeding
  • Augmentin ES-600 Drug Interactions
  • Augmentin ES-600 Support Group
  • 0 Reviews for Augmentin ES-600 - Add your own review/rating


  • Augmentin ES-600 Prescribing Information (FDA)

  • Augmentin ES-600 Suspension MedFacts Consumer Leaflet (Wolters Kluwer)

  • Augmentin MedFacts Consumer Leaflet (Wolters Kluwer)

  • Augmentin Prescribing Information (FDA)

  • Augmentin Consumer Overview

  • Augmentin XR Prescribing Information (FDA)

  • Augmentin XR Extended-Release Tablets MedFacts Consumer Leaflet (Wolters Kluwer)



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